Benfotiamine is a more bioavailable & physiologically active derivative of Thiamine. Unlike regular thiamine, a water-soluble nutrient also known as Vitamin B-1, Benfotiamine is a lipid (fat) soluble form of thiamine. Clinical research has shown that Benfotiamine's unique open-ringed structure, making it a fat-soluble nutrient, increases its bioavailability. &, Benfotiamine readily passes through intestinal mucosal cells, where it is converted into physiologically active thiamine.