4.3.2.1 Shape Up Day & Night has been formulated on the basis of Chronobiology; delivering nutrients to the body at the optimum time to ensure they work in synergy with the body's metabolism for maximum efficacy. 4.3.2.1. Shape Up Day & Night combines a day capsule for "get-up-&-go" & an extended time release night capsule, & ideal copmplement to a weight loss programme. 4.3.2.1 Shape Up Day & Night is even more effective because it contains Grapemax®, an extract obtained from viticulture (the quality cultivation of grapes), which improves the richness of its detoxifying active ingredients.