Glucosamine is an amino sugar found mainly in body tissues. it plays an important role in the formation of synovial fluids, tendons, ligaments, skin & bones. It's this formation of tissues that are used in the joints that makes glucosamine so useful in the treatment of osteoarthritis, joint mobility, joint pain & general joint health. A little known but important fact about glucosamine is its use in the formation of heart valve & blood vessel tissue, also making it very important for people with Heart & Circulatory problems. Glucosamine Hydrochloride provides 40% more glucosamine than the standard 2 K Cl form, is more bioavailable as well as being suitable for vegetarians & vegans, making it a far superior product. MSM (methylsulfonylmethane) is a naturally occurring organic sulphur used by the body to maintain joint & connective tissue health by being a key structural component of cartilage. Sulphur is the fourth most abundant mineral in the body & plays a major role in our overall health and General Wellbeing, helping protect against environmental toxins, parasites & allergens. Needed for the manufacture of many proteins, sulphur helps build strong hair, muscles, skin, bones teeth & collagen, so if you suffer from back-ache, neck-ache or general joint-ache MSM is just what you need. Because of these actions MSM is a perfect partner for Glucosamine. Glucosamine + MSM is the perfect combination for maintaining joint health & improving General Wellbeing all at the same time. It is recommended that 1500mg of glucosamine be taken on a daily basis, to ensure constant supply we recommend a divided dose throughout the day. MSM is easily destroyed so must be replaced on a daily basis.