Inner Armour Caffeine is perhaps the most widely used agent to mobilize fat for use as fuel, & one that actually helps burn that fat by elevating energy expenditure (basal metabolic rate). Several studies have shown that caffeine promotes lipolysis, the breakdown of stored fats into fatty acids which can be used by working muscle & other tissues for fuel while sparing glycogen in the process. Benefits:• Promotes lipolysis (the breakdown of stored fats) so they can be burned for energy• Promotes increased exercise performance & endurance• Spares glycogen (the muscle’s sugar energy stores) The traditional theory on how caffeine promotes lipolysis rests on the fact that at relatively high concentrations caffeine acts as a phophodiesterase inhibitor, maintaining elevated levels of c AMP (cyclic AMP) & in the process amplifying the effects of the body’s natural lipolytic hormones epinephrine & norepinephrine. During the lipolytic (fat mobilizing) signaling cascade, natural hormones like norepinephrine & epinephrine (or synthetic analogs like ephedrine or clenbuterol) bind to so-called alpha-1 & beta-1 & beta-2 adrenergic receptors on the surface of fat cells, activating cyclic Adenosine Monophosphate, or c AMP. c AMP ultimately acts to turn on the enzyme Hormone Sensitive Lipase (HSL). HSL breaks up stored fat so that it can be used for fuel. In addition, c AMP is deactivated by an enzyme called phosphodiesterase. Caffeine inhibits the action of phospodiesterase thereby prolonging lipolysis. Besides acting as a cutting agent, caffeine possesses ergogenic (sports performance enhancing) properties. The fat burning/glycogen sparing effect above may contribute to this. For adults of 18 years of age & over: 100-200mg not more than every 3 to 4 hours. Recommended daily dose: Take one tablet or as desired.