Lifesystems Expedition 50+ products contain a combination of dual action 50% DEET and natural pyerthroids therefore providing a high level of protection. The DEET is the active repellent, where as the pyerthroids actually act as a bite inhibitor meaning. Each application last up to 10 hours, however in areas of high humidity & temperature you may need to re apply i little bit sooner. Great for Jungle treks, & long haul trips in high risk Malaria areas. Dual formula DEET and Natural Pyrethroids Repels: Mosquitoes, midges, horseflies, sandflies, gnats, fleas ticks & other biting bugs up to 10 hours of protection